3-Chloro-4-methylphenyl isocyanate
3-Chloro-4-methylphenyl isocyanate
CAS: 28479-22-3
Molecular Formula: C8H6ClNO
3-Chloro-4-methylphenyl isocyanate - Names and Identifiers
3-Chloro-4-methylphenyl isocyanate - Physico-chemical Properties
| Molecular Formula | C8H6ClNO |
| Molar Mass | 167.59 |
| Density | 1.224 g/mL at 25 °C (lit.) |
| Melting Point | 20-24℃ |
| Boling Point | 107 °C/3 mmHg (lit.) |
| Flash Point | 229°F |
| Vapor Presure | 13.5Pa at 25℃ |
| Appearance | Liquid or Low Melting Solid |
| Color | Colorless to yellow |
| BRN | 2690771 |
| Storage Condition | 2-8°C |
| Sensitive | Moisture Sensitive |
| Refractive Index | n20/D 1.557(lit.) |
| Physical and Chemical Properties | This product is a solid, soluble in chlorobenzene solution, water decomposition. |
3-Chloro-4-methylphenyl isocyanate - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R42 - May cause sensitization by inhalation |
| Safety Description | S23 - Do not breathe vapour. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2206 6.1/PG 3 |
| WGK Germany | 1 |
| TSCA | Yes |
| HS Code | 29291090 |
| Hazard Class | 6.1 |
| Packing Group | II |
3-Chloro-4-methylphenyl isocyanate - Reference Information
| LogP | 3.78 |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| Uses | 3-chloro-4-methylphenyl isocyanate is an intermediate of the herbicide chlorotoluron. |
| production method | the preparation method is to add chlorobenzene into the reaction kettle, pass a certain amount of phosgene under cooling, then drop the chlorobenzene solution of 3-chloro -4-methylaniline into the reaction kettle, after adding, continue stirring for a certain period of time, then transfer the material into the hot reaction kettle, continue to pass phosgene, and slowly heat up. At this time, a large amount of hydrogen chloride and phosgene escape. After condensation, chlorobenzene is used to absorb the tail gas, enter the tail gas treatment system, and continue to pass into the phosgene reaction until the material is transparent liquid. The reaction is over, and nitrogen is introduced to drive out the material. The hydrogen chloride and the remaining phosgene in the gas are the end of the gas drive until there is no phosgene and only a trace of hydrogen chloride. Then move the material to the desolubilization kettle to dedissolve to obtain the finished product. |
| category | toxic substances |
| flammability hazard characteristics | combustible; combustion produces toxic chloride and nitrogen oxide gas |
| storage and transportation characteristics | warehouse ventilation and low temperature drying; Separate storage and transportation from oxidants, acids and food |
| fire extinguishing agent | dry powder, sand, foam, carbon dioxide |
Last Update：2024-04-10 22:29:15
